Primary and secondary outcomes
The primary outcome was the annualized rate of the AAR in all cohorts. Secondary outcomes included the rate of anaphylaxis. Additionally, this study examined the abovementioned outcomes in children who completely avoided allergic foods, the symptoms, required treatment, site where the AAR developed, causes of AAR, risk factors for the AAR experienced, and the difference between those with low-dose reactivity and low-dose tolerance in the rate of AAR.