Allergic reaction and management of food allergy
Symptoms were categorized according to the organ system, and symptom severity was classified as mild, moderate, or severe.4The clinical criteria for anaphylaxis diagnosis were defined by the World Allergy Organization in 2011.16 For children with an unconfirmed diagnosis of food allergy or undetermined threshold, a low-dose (≤250, ≤102, ≤53, or ≤133 mg HE, CM, wheat, or peanut protein, respectively) OFC, was performed initially. Patients who passed the low-dose OFC were instructed to consume the low dose 2–3 times per week, which was to include food that was cooked or processed at home. Thereafter, a stepwise OFC was performed.4,17,18Acquired tolerance to allergic food was defined as the state in which patients completed a full-dose OFC (6200, 6800, 5300, or 2660 mg for HE, CM, wheat, or peanuts protein, respectively) and were able to consume the same dose at home.