Overall cohort (n = 1096) HE (n = 609) CM (n = 457) Wheat (n = 138) Peanut (n = 90)
Annualized rate of an accidental allergic reaction (95% CI)
0.130 (0.109–0.153) 0.107 (0.082–0.136) 0.124 (0.094–0.161) 0.087 (0.044–0.151) 0.111 (0.053–0.204)
Annualized rate of anaphylaxis for accidental allergic reaction (95% CI)
0.015 (0.009–0.025) 0.005 (0.001–0.014) 0.019 (0.009–0.037) 0.014 (0.002–0.052) 0.011 (0.0002–0.041)
Accidental allergic reactions, n 148 61 57 12 8
Severity of symptoms, n (%)
Mild 65 (44%) 24 (39%) 27 (47%) 4 (33%) 4 (50%)
Moderate 76 (51%) 32 (52%) 29 (51%) 7 (58%) 4 (50%)
Severe 1 (0.7%) 0 (%) 1 (2%) 0 (0%) 0 (0%)
Unknown 6 (%) 5 (8%) 0 (0%) 1 (8%) 0 (0%)
Symptoms, n (%)
Skin 68 (46%) 25 (41%) 29 (51%) 5 (42%) 4 (50%)
Oral mucosal 31 (21%) 10 (16%) 14 (25%) 1 (8%) 4 (50%)
Respiratory 32 (22%) 9 (15%) 16 (28%) 4 (33%) 1 (%)
Gastrointestinal 36 (24%) 23 (38%) 6 (11%) 3 (25%) 2 (25%)
Cardiovascular 3 (2%) 1 (2%) 2 (4%) 0 (0%) 0 (0%)
Neurological 3 (2%) 2 (3%) 0 (0%) 0 (0%) 1 (%)
Treatments, n (%)
Total treatments 101 (68%) 41 (67%) 39 (68%) 10 (83%) 6 (75%)
Antihistamine 84 (57%) 40 (66%) 31 (54%) 10 (83%) 5 (63%)
Steroids 11 (7%) 3 (5%) 6 (11%) 1 (8%) 1 (13%)
β2-agonist inhalation 5 (3%) 0 (0%) 2 (4%) 2 (17%) 1 (13%)
Intramuscular adrenaline 6 (4%) 0 (0%) 6 (11%) 0 (0%) 0 (0%)