Annualized rate of AAR and anaphylaxis
A total of 143 of 1,096 (13%) participants experienced 148 AAR. The annualized rates of AAR and anaphylaxis were 0.130 and 0.015 in all cohorts, 0.107 and 0.005 for HE, 0.124 and 0.019 for CM, 0.087 and 0.014 for wheat, and 0.111 and 0.011 for peanut allergies (Table 2). Among the patients who completely eliminated allergic foods, the rates of AAR and anaphylaxis were 0.162 and 0.035 in the overall cohort, 0.127 and 0.018 for HE, 0.167 and 0.037 for CM, 0.102 and 0.034 for wheat, and 0.166 and 0.014 for peanut allergies, respectively (Supplementary Table S1).