Impact statement
This study focused on accidental allergic reactions (AAR) in Japanese
children with immediate-type food allergies. Although the annualized
rate of AAR was relatively low, our findings reveal that half of the
affected children experienced moderate to severe reactions. Furthermore,
identifying low-dose reactivity as a risk factor for AAR could have
practical implications for pediatricians and allergists, emphasizing the
importance of careful risk management. This research contributes to a
better understanding of AAR in children, potentially improving the
safety and care of young patients with food allergies.