The study cohort included patients with multiple food allergies,
including a combination of HE, CM, wheat, and peanut allergies. Total
IgE and antigen-sIgE levels were converted to log 10
values, which were used in the analysis. †Antigen-sIgE levels indicate
egg white- or milk-sIgE levels. Multiple logistic regression analysis
was performed in A) all cohorts, (B) HE allergy, and (C) CM allergy,
respectively. Patients with wheat or peanut allergies were ineligible
for inclusion in the multiple logistic regression analysis because of
the small sample size. Additionally, for HE or CM allergies, egg white-
and ovomucoid-sIgE or milk- and casein-sIgE levels would have been
collinear. Therefore, egg white and milk sIgE levels were used as
variables in the multiple logistic regression analysis of outcomes as
shown in Supplementary Table S5. HE, hen’s egg; CM, cow’s milk