Allergic reaction and management of food allergy
Symptoms were categorized according to the organ system, and symptom
severity was classified as mild, moderate, or severe.4The clinical criteria for anaphylaxis diagnosis were defined by the
World Allergy Organization in 2011.16 For children
with an unconfirmed diagnosis of food allergy or undetermined threshold,
a low-dose (≤250, ≤102, ≤53, or ≤133 mg HE, CM, wheat, or peanut
protein, respectively) OFC, was performed initially. Patients who passed
the low-dose OFC were instructed to consume the low dose 2–3 times per
week, which was to include food that was cooked or processed at home.
Thereafter, a stepwise OFC was performed.4,17,18Acquired tolerance to allergic food was defined as the state in which
patients completed a full-dose OFC (6200, 6800, 5300, or 2660 mg for HE,
CM, wheat, or peanuts protein, respectively) and were able to consume
the same dose at home.