In Staphylococcus aureus, the acyl-CoA synthetase MbcS supports branched-chain fatty acid synthesis from carboxylic acid and aldehyde precursors
Marcelle C. dos Santos Ferreira, Augustus Pendleton^, Won-Sik Yeo, Fabiana C. Málaga Gadea, Danna Camelo, Maeve McGuire and Shaun R. Brinsmade#
Department of Biology, Georgetown University, Washington, DC, USA
Running title: MbcS-dependent BCFA synthesis in Staphylococcus aureus
^Present address: Department of Microbiology, Cornell University, Ithaca, NY, USA
#Address correspondence to Shaun R. Brinsmade,shaun.brinsmade@georgetown.edu
Key words: Staphylococcus aureus , MRSA, branched-chain fatty acids, BKDH complex, membrane phospholipids, fatty acids metabolism.