Histological sections of Peyer’s patches from male Wistar rats of the
groups Control - CT (A), Bisphenol A - BPA (B), Bisphenol A + Selenium -
BPA + Se (C) and Selenium - SE (D) stained by Masson’s trichrome method.
The presence of lymphocytes (arrowhead), leukocyte groups (circle) and
macrophages (*) was observed in all groups studied. Scale bars: 1000x
magnification.
At higher magnification (1000x), leukocytes of varying sizes and
staining intensities were observed. After measurement, it was observed
that there was a significant reduction (p < 0.05) in the
number of defense cells in the PP’s in the BPA group (30.08±1.87) when
compared to the other groups (TC: 38.72±3.30; BPA+Se: 37.56±2.61; If:
38.36±1.98) (Figure 6). However, a greater presence of macrophages was
observed in the BPA and BPA+Se groups. No significant differences in the
number of immune cells were observed in the other groups.
Figure 6. Number of leukocytes in Peyer’s patches.