Histological sections of Peyer’s patches from male Wistar rats from the groups Control - CT (A), Bisphenol A - BPA (B), Bisphenol A + Selenium - BPA + Se (C) and Selenium - SE (D). RF: Follicular Region; RIF: Interfollicular Region; (*) inflammatory vacuoles. Scale bars: 40x increase.

In the CT group, it was observed that the histological structure of the epithelial layer of the PP´s is of the simple cylindrical type (Figure 2 A-B), with the presence of mucus-producing cells (goblet cells), enterocytes with brush borders indicating a certain absorptive function, and the presence of intraepithelial lymphocytes. It was also possible to observe the presence of lymphocytes in the follicular region with intact parenchyma, and with the absence of vacuoles in its structure.