Author Contributions
ΨThese authors contributed equally to this study. Xueqiong Wu and Yan Liang designed the research study. Yan Liang, Yourong Yang and Lan Wang performed the animal experiments including mouse PBMCs isolation, RNA extraction and gene microarray assay. Nan Wang and Xueqiong Wu analyzed the data and performed bioinformatics analysis. Nan Wang, Qianqian Ma, Jie Mi and Yong Xue performed human PBMCs isolation and RT-qPCR validation assay. Nan Wang performed the GEO validation. Nan Wang and Xueqiong Wu wrote the manuscript. Xueqiong Wu reviewed and revised the manuscript and supervised the project and original data.