Statistical analysis
The statistical analysis was performed using statistical package STATA
version 14. A p value of 0.05 or less (<=0.05) was considered
statistically significant. The power of study was 80% and alfa was
0.05.
Descriptive statistic was reported as mean, standard deviation,
percentage and frequency. Confidence interval was 0.95 (Cl, 0.95).
Independent samples T test and chi-square test was used to compare the
differences between Baseline characteristics of two groups.
Linear regression analysis was used to investigate the relationship
between continues outcomes and treatment. Besides, a logistic regression
was used to investigate the relationship between binary dependent
variables and treatment. Adjustment for severity was performed by
multiple linear and multiple logistic regression.