##Animals
The 6 weeks-age of male Sprague-Dawley rats weighing 160–180 g were
purchased from the Laboratory Animal Center of the Academy of Military
Medical Sciences (Beijing, China). The animals were placed in a
humidity- and temperature-controlled environment, with a light cycle of
12 h, with 3 animals in each cage, and free access to food and water.
Experiments
were performed under a project license (No. IRM-DWLL-2020019) granted by
Ethics Committee of the Institute
of Radiation Medicine, Chinese Academy of Medical Science & Peking
Union Medical College, in compliance with institutional guidelines for
the care and use of animals. A protocol was prepared and passed our
team’s proposal report before the study, while with no registration as
it’s not a clinical trial.