3.2 Effect of Tubee on mRNA expression of inflammatory factors
in mice organs
The mRNA levels of inflammatory factors IL-1β, IL-6, TNF-α, and iNOS
were significantly higher in the liver, spleen, and lung of mice in the
model group, indicating that all organs in the model group had different
degrees of inflammatory responses (Figure 3A-D). IL-6, and iNOS were
significantly lower in the liver, spleen, or lung of mice that were
injected intraperitoneally with Tube compared with the model group, as
well as IL-1β in liver and lung. However, the mRNA levels of TNF-α were
not significantly different across organs.