3.5 Effect of Tube on classical cell signaling pathway-related proteins
The phosphorylation levels of NF-κB p65, MAPK p38, ERK, and JNK were significantly higher in the model group compared with the blank control group (Figure 7 ). There was no significant difference in the phosphorylation levels of NF-κB p65, MAKP p38, ERK, or JNK between the Tube and model groups over time, suggesting that the anti-inflammatory effect of Tube may not be significantly associated with the classical NF-κB signaling pathway.