E. multilocularis infection can cause liver injury.
In order to determine whether E. multiloculari s infection can
cause liver damage. we used HE staining method to detect the liver
pathological damage. The results showed that the mice in the infection
group had obvious lesions in the liver and granulocytes gathered around
the lesions compared with control group(Fig
2A). The results of Masson staining showed that there were a large
amount of collagen fiber deposition in the liver tissue of mice in the
infection group(Fig 2B). In addition, The
levels of AST and ALT in the serum of mice in the infection group were
significantly higher than those in the control
group(Table2 and
Fig 2C). This results suggested thatE. multiloculari s parasitism can cause damage to liver tissue.