miRNAs differential expression
E. multiloculari s infection can cause liver damage in mice, but
the mechanism of damage is still unclear. This study mainly explores the
mechanism of liver injury from the regulation of miRNAs. The mouse liver
tissue close to the lesion site was isolated for transcriptome
sequencing. A total of 71 differentially expressed miRNAs were screened
out(Fig3B-D, Table S1), and deleted of
non-mouse miRNAs, there are 36 miRNAs among them with a large difference
of
|FC|>0.585(Table3),
and these miRNAs may be related to liver damage caused by E.
multiloculari s.