PE VS Normotensive
Five studies (293612 twin pregnancies) explored the risk of birthweight discordance (≥15%) in twin pregnancies with PE compared to Normotensive group. It turned out that the risk of birthweight discordance was significantly higher in twin pregnancies with PE (OR 1.66, 95% CI 1.32-2.08; I2 =64%). Birthweight discordance was associated was PE in DC (OR 2.74, 95% CI 2.09-3.61; I2 =40%) but not in MC (OR 1.21, 95% CI 0.68-2.15; I2 =0%) twin pregnancies based on the stratification by chorionicity. (Figure 3)