RESULTS
A total of 130 patients were included in this study. Patients were divided into 2 groups: survived and deceased. There were 55 patients (with a mean age of 64.76-14.93 years, 58.18% male, 41.12% female) in the survived group, while there were 75 patients (with a mean age of 65-15 years, 58.67% male, 41.33% female) in the deceased group. There was no difference between the groups in terms of age and gender. While there was no difference between the groups in terms of hypertension, diabetes mellitus, and cerebrovascular disease, the number of patients in the deceased group was statistically higher in terms of asthma (p:0.030) and COPD (p:0.003). The baseline clinical and laboratory characteristics of the groups are shown in Tables 1 and 2.
The comparison of laboratory characteristics showed that the deceased group had higher CK-MB (60.88-46.99 vs. 30.55-21.77, p: 0.000), troponin (106-64.02 vs. 39.87+-14.36, p: 0.000), LDH (554.61-209.22 vs. 365.24+-155.47 p: 0.000), CRP (127-75.32 vs. 87.4-68.24, p: 0.001), leukocyte (13.01- 4.87 vs. 8.82-4.84, p: 0.000) and D-dimer values (25.29+-23.09 vs. 1.18+-1.06, p: 0.000).
The electrocardiographic and echocardiographic characteristics are shown in Table 3. There was no difference between the groups in terms of heart rate (83.21-19.16 vs. 86.51-17.06, p: 0.290), TPAVR (-0.07+0.26 vs. 0.12+-0.8, p: 0.65), P-R interval (107.51+-7.30 vs. 109+-23.52, p: 0.173), QRS interval (110.52+- 5.71 vs. 112.15+- 9.42, p: 0.333), QT (393.73+-42.85 vs. 382.22+-27.63, p: 0.11) and QTc intervals (393.73+-42.85 vs. 382.22+-27.63, p: 0.388), and STAVR/TPAVR ratio (1.58+-0.79 vs. 1.62+-0.62, p: 0.739). Positive TaVR (28 patients in the deceased group, 5 patients in the survived group, p:0.000) and STAVR (0.15+-0.6 vs. 0.19+-0.12, p: 0.002) were statistically significant in the deceased group. There was no difference between the groups in terms of left ventricular ejection fraction (p: 0.05). The univariate and multivariate regression analyses showed that positive TAVR (OR: 5.151, 95% CI: 1.001-26.504, p: 0.0012), lactate dehydrogenase (LDH) (OR: 1.006, 95% CI: 1.001-1.010, p: 0.012) and D-dimer (OR:1.436, 95% CI: 1.115-1.848, p: 0.005) were independent risk factors for mortality. (Table 4)