Table 2. Associations of regular use of PPI with the risk of chronic kidney disease
Cases/ Person-years Hazard Ratio [95% Confidence Interval] Hazard Ratio [95% Confidence Interval] Hazard Ratio [95% Confidence Interval]
Age and gender stratified model Multivariable adjusted model 1 Multivariable adjusted model 2
PPI use
Non-regular PPI user 5630/3417548 1.00[Reference] 1.00[Reference] 1.00[Reference]
Regular PPI user 1661/366674 2.15[2.03, 2.27] 1.24[1.17, 1.31] 1.24[1.16, 1.33]