Clinical outcomesÂ
Three patients died during the study. One patient died due to graft
failure and another due to IPA, in the third case of death fungi was not
detected in the last bronchoalveolar lavage available.
Two patients affected by CF who suffered fungal lung colonization did
not have exacerbations requiring antifungal treatment or hospitalization
during the time of the study. One patient receiving nebulized
voriconazole as prophylaxis after LT had an adequate clinical evolution
during the follow-up. There were three cases of microbiological response
and voriconazole resistance was developed in one case.