Sample size calculation
In a cohort of 2300 patients and for a normally distributed continuous outcome (i.e. ultrasound and biochemical parameters, birth weight), it is possible to detect with a type I error of 5% and a type II error of 20% (power 80%) a difference of 0.24 SD and 0.16 SD if 10% and 50% of all subjects has the relevant exposure respectively (i.e. nutritional score > 6).