Fig.S2: Expression patterns of genes in MHV-1 infected obese vs lean C3H/HeJ mice, based on raw counts data.
Biomarker genes were identified after comparing the mouse RNAseq data to severe vs mild COVID-19 patient data. Then iDEP 2.0 was used to perform gene plots on raw counts, with standard deviation, for the identified genes between MHV-1 infected obese and lean mice. B4galt5, Flt1, Stx3 and Ass1 showed a trend towards upregulation, while Crip2 and Rora showed a trend towards downregulation in obese vs lean mice.