3.1 Sample Demographic together with Clinical Profiles
There were no variations among the 4 groups with respect to gender or smoking status. We found major variations for age, marital status, employment status, as well as educational level .The results showed that the ReSch group had more positive symptoms and negative symptoms as well as general psychiatric symptoms than the FEP group, while the FEP group also had more positive symptoms and negative symptoms than the UHR group. In addition, the GAF results of the HC, UHR FEP and ReSch groups decreased gradually, whereas the MADRS total scores of the HC, UHR, FEP and ReSch groups increased gradually.