Conclusion
In summary, differential expression analysis, WGCNA, and GO analysis highlighted several transcripts in B-ALL. Here, we indicated the upregulation of SPRING1 in B-ALL patients compared to ITP samples for the first time. The findings propose that SPRING1 directly affects cholesterol metabolism. However, further functional and clinical analysis are needed to fully understand the role of SPRING1 in B-ALL.
Acknowledgments The authors wish to thank their colleagues at the Mashhad Academic Center for Education, Culture, and Research (ACECR) for the kindest collaboration.