Conclusion
In summary, differential expression analysis, WGCNA, and GO analysis
highlighted several transcripts in B-ALL. Here, we indicated the
upregulation of SPRING1 in B-ALL patients compared to ITP samples
for the first time. The findings propose that SPRING1 directly
affects cholesterol metabolism. However, further functional and clinical
analysis are needed to fully understand the role of SPRING1 in
B-ALL.
Acknowledgments The authors wish to thank their colleagues at the Mashhad Academic
Center for Education, Culture, and Research (ACECR) for the kindest
collaboration.