Patients and ethics statement
Bone marrow mononuclear cells (BMMNCs) samples were obtained from 20
B-ALL patients and 20 non-malignant ITP (immune thrombocytopenic
purpura) patients who had not received any chemoradiotherapy before
aspiration and had no history of any cancer type, respectively.
Specimens were obtained from Dr. Sheikh Children’s Hospital of Mashhad
University of Medical Sciences (MUMS), Mashhad, Iran. All individual
participants signed informed consent forms prior to their inclusion in
the study. The ethics committee of the Ferdowsi University of Mashhad,
Mashhad, Iran approved the research protocol (ethical code:
IR.UM.REC.1400.058) and it was performed following the Helsinki
Declaration.