Figure 2. Binding mode diagram of TPEARG and arginase (PDB: 2CEV) . (A) Binding of TPEARG molecule on the hydrophobic surface of arginase, blue and orange indicate the hydrophilic and hydrophobic parts of the protein surface, respectively. (B) Two-dimensional binding mode of TPEARG molecule and arginase, green dashed line indicates hydrogen bonding interaction, purple solid line indicates ligand interaction, red gear-like indicates hydrophobic interaction. (C) Position of TPEARG molecule in the three-dimensional structure of arginase. (D) Three-dimensional binding mode diagram of fluorescent probe molecule and arginase, green dashed line indicates hydrogen bonding interaction.