Introduction
There is a growing interest in cardiac electrophysiology studies with a
particular focus on cardiac ion channelopathies and sudden cardiac death
(SCD) in diverse populations. Previous research studies have shown
disparities in the management of arrhythmias and treatment effectiveness
in various ethnic groups, including African American (AA)/Black and
Asian populations, but only limited data exists for Hispanic/Latino and
Indigenous groups.1-3 Moreover, health disparities
that could impede the detection of these arrhythmias in these two
populations have yet to be fully explored. The goal of this review is to
advance our understanding of the fundamental aspects of cardiac
pathophysiology and shed light on potential population-specific factors
influencing susceptibility to SCD. This ultimately leads to targeted
interventions and therapeutic strategies tailored to different
populations at risk of cardiac arrhythmias and SCD.