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\begin{document}

\title{Research progress on meningeal metastasis of lung cancer}



\author[1]{Peiqiang Liang}%
\affil[1]{Shaoguan First People's Hospital}%


\vspace{-1em}



  
  \date{May 24, 2024}


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\begin{abstract}
Meningeal metastases (LM) are a common complication of malignant tumors
that progress rapidly and have a poor prognosis. Meningeal metastasis
may be a combination of intracellular and extracellular factors. The
linkage between the C3 signaling pathway and the EGFR ligand regulatory
protein pathway may be one of the reasons why NSCLC patients with EGFR
mutations are prone to brain/meningeal metastasis. Cerebrospinal fluid
cytology is the gold standard for diagnosing meningeal metastases. There
are various clinical treatment options, including chemotherapy,
radiation therapy, immunotherapy, targeted therapy, and so on. The
incidence rate of meningeal metastatic carcinoma is increasing year by
year. This article reviews the research progress in pathogenesis,
diagnosis and treatment of meningeal metastatic carcinoma of lung
cancer.%
\end{abstract}%



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