Derived asthma phenotypes and their descriptive names
Based on the DEC computational metrics, a three-cluster solution had the best metrics, but when subjected to a clinical review, we determined that a four-cluster solution was the most meaningful and valid representation of the data, both clinically and scientifically, capturing the diversity of phenotypes, hence we chose the four-cluster solution. The clusters were given the following descriptive names:
Detailed information on differences between clusters can be found in the supplementary material.